报告题目🏷：Towards Natural Product-Based Therapeutics
报告人： Prof. Matthew Shair
报告时间：2014年9月26日（星期五）下午2:00
报告地点：天美代理中北校区化学馆A-205报告厅
报告人简介👩👩👦👦🎍：Matthew Shair教授是国际知名的有机化学家，在天然产物全合成领域享有盛誉。
2002 Professor (with Tenure) Harvard University;
1993-1995: Columbia University; Ph.D. in Organic Chemistry;
1990-1993: Yale University; M.S., Research advisor: Prof. Samuel J. Danishefsky;
1986-1990: University of Rochester; B.S. in Chemistry with distinction.
报告内容： Our research has been focused on “protein structure and function and its regulation through chemicals” in the direction of "chemical probe and target validation", which is a cutting research in the field of Chemical Biology. We have uncovered the molecular mechanisms and chemical regulations of several important proteins, which interact with biological macromolecules, including nucleic acid demethylases, redox-sensing transcriptional regulators, and virulence factors by using small molecule tools. These studies thus help to understand the biological pathways better, and obtain active compounds as well as target candidates for drug discovery.
报告时间：2014年9月26日（星期五）下午2：00